First university-wide Supercomputer for Newcastle
HPC machine supports wide range of applications, including flood simulations and brain geometry
Posted by Rebecca Paddick | July 13, 2018 | Technology
newcastle-university, supercomputer, hpc, high-performance-computing´

Researchers at Newcastle University are benefitting from a new High Performance Computing (HPC) machine, called Rocket. 

Newcastle University has purchased the centralised HPC system to support all researchers across the University and replace existing departmental clusters as they come to end of life.

 The new HPC system is designed, integrated and configured by high performance compute, storage and data analytics integrator, OCF.  The £2 million investment is funded by the University, supporting its dedication to providing world-class research facilities for its existing academics and attracting new researchers to the University.

With Rocket, the University aims to establish a ‘HPC culture’, encouraging cross-departmental research and collaboration and helping it remain a world-class research institution.  Over 200 users are already benefitting from Rocket, including academics, researchers, staff and students from over 15 University departments, including medical, neuroscience, chemistry, biology, physics, mathematics, engineering, computing, business and geography.

“Workloads are driving an ever-growing set of data intensive challenges that can only be met with accelerated infrastructure,” said Werner Hofer, Dean of Research & Innovation at Newcastle University. ”Rocket provides the significant memory and fast processing we need for bulky, complex numerical computation. My post-doctoral researcher was able to process half a million CPU hours’ worth of calculations which was not at all possible with our previous processing power.”

Previously, what would take researchers sometimes months, even years to process using a single desktop computer can be run on Rocket as high-volume simulations, generating outcomes in a significantly reduced timeframe, saving valuable time and budget.

Rocket in action

  • Assessing the extent of changes in flood simulation can now be simulated in 11 hours rather than 18 days on a desktop computer by using a change quantification algorithm.
  • Brain geometry which used to take the equivalent of 270 people years can now be performed in just a few hours.
  • Drug testing can be done with preliminary ‘in silicon’ research rather than ‘in vitro’, significantly reducing the need for animal research as computational chemistry is used to model and predict compounds which will be effective drugs.
  • Using Deep Learning for the early detection of respiratory disease in pigs takes only two days to carry out 17,250,000 particle evaluations. This method used outperforms any other method and drastically improves time for Particle Swarm Optimisation (PSO).
  • Identifying genetic mutation in genomes arising in cancerous cells. With Rocket, the run time for 30 genomes is now 12 hours compared to 28 days if it was run on a single core. The pipeline identified 100% of cancer-causing mutations creating the potential for more accurate, faster, targeted diagnosis of leukaemia types, resulting in improved, targeted treatment and better outcomes for patients.
  • Identifying rare genetic diseases, Rocket can compare whole-exome sequences, looking for alignment and variant (across millions of sequences per genome), making it possible to search almost the entire protein coding region of a patient’s genome for nuclear genetic defects in one experiment in approximately one day. 

“With OCF as our partner, we have access to the skills and knowledge we need to create our HPC system,” said Martin Edney, Faculty IT Manager at Newcastle University. “From inception, to design, consultancy and implementation, OCF has the in-depth experience to ensure Rocket meets the needs of every University department. The ongoing support service means that OCF is always on hand for expert guidance and support.”

“We have a data explosion in every single aspect of science and society and we need the appropriate computational resources to be able to process this data,” said Dr Jaume Bacardit, Reader in Machine Learning at Newcastle University.

“People have to spend a lot of time writing proposals to get access to the big national or regional supercomputers so it’s a lot of work for us as academics. It’s much easier for us if we can just have a local machine that we can use,” said Dr Tamara Rogers, Reader in Computational Astrophysics at Newcastle University.

The pilot phase for Rocket began in September 2017 and it went live on 31 October 2017. See here for further information about Rocket.